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Total results with these characteristics: 213

Disease: Pneumococcus

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Moving the Needle

This quarterly e-newsletter provides updates from PATH’s Center for Vaccine Innovation and Access on its vaccine development efforts, as well as related supporting work, such as developing human challenge models, building capacity of …

Author: PATH

Multinational Study of Pneumococcal Serotypes Causing Acute Otitis Media in Children

This study analyzed nine existing datasets comprising pneumococcal isolates from middle ear fluid samples collected from 1994 through 2000 from 3,232 children with AOM from Finland, France, Greece, Israel, several East European countries, the US …

Author: Hausdorff WP, Yothers G, Dagan R, et al.

Publication date: 2002

Multivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid With Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection

This article, published in Clinical and Vaccine Immunology, reports on the results of a study that examined the protective immunogenicity of three pneumococcal proteins in various combinations in a mouse model, in the effort to contribute to the …

Author: Chen A, Mann B, Gao G, et al.

Publication date: 2015

Nasopharyngeal Carriage of Streptococcus pneumoniae in Pneumonia-Prone Age Groups in Semarang, Java Island, Indonesia

This article, published in PLOS One, presents results from a population-based survey conducted to investigate nasopharyngeal carriage of Streptococcus pneumoniae in Semarang, Indonesia. The authors conclude that the limited coverage of commercially …

Author: Farida H, Severin JA, Gasem MH, et al.

Publication date: 2014

Nasopharyngeal Microbial Interactions in the Era of Pneumococcal Conjugate Vaccination

This article, published in Vaccine, reviews data on co-colonization of pathogens in the nasopharynx, focusing on Streptococcus pneumoniae and the impact of pneumococcal vaccination. The authors conclude that pneumococcal vaccination has not had a …

Author: Dunne EM, Smith-Vaughan HC, Robins-Browne RM, Mulholland EK, Satzke C

Publication date: 2013

National Center for Immunization and Respiratory Diseases (NCIRD)

The mission of the National Center for Immunization and Respiratory Diseases (NCIRD) is the prevention of disease, disability, and death through immunization and by control of respiratory and related diseases. This web page contains additional …

Author: US Centers for Disease Control and Prevention

New Conjugate Vaccines for the Prevention of Pneumococcal Disease in Developing Countries

This article, which appeared in Drugs of Today, provides an overview of currently available pneumococcal conjugate vaccines (PCVs) and outlines several new approaches in the pipeline for PCVs designed to meet needs in the developing world. ABSTRACT …

Author: Ginsburg AS, Alderson MR

Publication date: 2011

NUVI - Resources for Monitoring and Surveillance

This web page provides links to numerous resources related to disease burden monitoring and surveillance from the World Health Organization's (WHO's) New and Under-utilized Vaccines Implementation (NUVI) program. NUVI focuses specifically on …

Author: World Health Organization

One Is Too Many: Ending Child Deaths From Pneumonia and Diarrhoea

This report highlights the current burden of pneumonia and diarrheal disease in children under the age of five and outlines the protective, preventative, and treatment interventions available to fight these diseases. It explains current progress in …

Author: United Nations Children’s Fund

Publication date: 2016

Optimising the Use of Conjugate Vaccines to Prevent Disease Caused by Haemophilus influenzae type b, Neisseria meningitidis, and Streptococcus pneumoniae

This article, published in Vaccine, reviews the state of the current evidence on conjugate vaccines and identifies important areas for further study, in order to inform the debate regarding the best use of these vaccines, which not only prevent …

Author: Trotter CL, McVernon J, Ramsay ME, et al.

Publication date: 2008

Optimum Dosing of Pneumococcal Conjugate Vaccine For Infants: A Landscape Analysis of Evidence Supporting Different Schedules

This supplement of the Pediatric Infectious Disease Journal features nine articles on the considerations for pneumococcal conjugate vaccine (PCV) dosing schedules. This systematic literature review and corresponding analyses support the dosing …

Author: O’Brien KL, Goldblatt D, Whitney CG, eds.

Publication date: 2014

Options for Inactivation, Adjuvant, and Route of Topical Administration of a Killed, Unencapsulated Pneumococcal Whole-Cell Vaccine

This article, published in Clinical and Vaccine Immunology, describes research conducted at Children’s Hospital Boston which showed that killing cells of a noncapsulated strain of Streptococcus pneumoniae with chloroform, tricholorethylene, or …

Author: Lu Y-J, Yadav P, Clements JD, et al.

Publication date: 2010

Outcome of Meningitis Caused by Streptococcus Pneumoniae and Haemophilus influenzae type b in Children in the Gambia

Published in the journal Tropical Medicine and International Health, the purpose of this study was to assess the importance of disabilities following pneumococcal and Hib meningitis in The Gambia. 257 children aged 0-12 years hospitalized between …

Author: Goetghebuer T, et al.

Publication date: 2000

PATH Pneumococcal Vaccine Project

This paper, published in Pediatric Health, provides an overview of the efforts that PATH is undertaking to advance the development of new vaccines against Streptococcus pneumoniae that can be low-cost and accessible for the developing world. …

Author: Alderson MA, Maisonneuve J, Newhouse LC, Boslego JW

Publication date: 2010

Pathogenesis, Treatment, and Prevention of Pneumococcal Pneumonia

This article, published in The Lancet, summarizes the past ten years of research on pneumococcal pneumonia. The article includes a review of the epidemiology, genetics, and immunology of the disease, as well as approaches to clinical diagnosis, …

Author: van der Poll T, Opal SM

Publication date: 2009

Pediatric Bacterial Meningitis Surveillance--African Region, 2002 to 2008

This article, published in Morbidity and Mortality Weekly Report, analyzes data for 2002 to 2008 from the Pediatric Bacterial Meningitis (PBM) Surveillance Network, which collects information on laboratory-confirmed bacterial meningitis cases among …

Author: US Centers for Disease Control and Prevention

Publication date: 2009

Pediatric Invasive Pneumococcal Disease in the United States in the Era of Pneumococcal Conjugate Vaccines

This article, published in Clinical Microbiology Reviews, discusses the epidemiology of serious and invasive pneumococcal infections in the United States in the pneumococcal conjugate vaccine era and reviews some of the pneumococcal vaccines that …

Author: Tan TQ

Publication date: 2012

The Pharmacoeconomics of Pneumococcal Conjugate Vaccines in Latin America

This article, published in Vaccine, aims to provide a framework for the global evaluation of pneumococcal conjugate vaccines by reviewing the pharmacoeconomic perspective in Latin America, highlighting both the strengths and weaknesses, while also …

Author: Giglio N, Micone P, Gentile A

Publication date: 2011

Physical Characterization and Formulation Development of a Recombinant Pneumolysoid Protein-Based Pneumococcal Vaccine

Pneumolysin is a protein toxin produced by virtually all invasive strains of S. pneumoniae and is considered an important virulence factor. It is immunogenic and has the potential to be a new vaccine antigen offering broad serotype-independent …

Author: Hu L, Joshi SB, Liyanage MR, et al.

Publication date: 2013

The Pink Book—Epidemiology and Prevention of Vaccine-Preventable Diseases

This book provides physicians, nurses, nurse practitioners, physician assistants, pharmacists, and others with the most comprehensive information on vaccine-preventable diseases. In addition to chapters on more general vaccine-related topics, it …

Author: US Centers for Disease Control and Prevention

Publication date: 2015

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