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Disease: Rotavirus

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Impact of Rotavirus Vaccine on Childhood Diarrheal Hospitalization Following Introduction Into the South African Public Immunization Program

This article, published in the Pediatric Infectious Disease Journal, describes a study in South Africa that demonstrated dramatic decreases in diarrhea-related hospitalizations in infants and young children in both rural and urban settings in the …

Author: Msimang VMY, Page N, Groome MJ, et al.

Publication date: 2013

Impact of Withholding Breastfeeding at the Time of Vaccination on the Immunogenicity of Oral Rotavirus Vaccine—A Randomized Trial

This article, published in PLOS One, reports on the results of a study that examined the immune effect of withholding breastfeeding one hour before and after administration of the live, oral, monovalent rotavirus vaccine, Rotarix®, in infants in …

Author: Ali A, Kazi AM, Cortese MM, et al.

Publication date: 2015

Incidence of Rotavirus and Circulating Genotypes in Northeast Brazil During 7 Years of National Rotavirus Vaccination

This article, published in PLoS One, examined rates of rotavirus infection before and after rotavirus vaccine introduction in Brazil in 2006. The authors found that the vaccine was associated with substantial reductions in rotavirus incidence and …

Author: Gurgel RQ, Alvarez AJ, Rodrigues A, et al.

Publication date: 2014

Indian Academy of Pediatrics Advisory Committee on Vaccines and Immunization Practices

This website from the Indian Academy of Pediatrics provides up-to-date information on vaccination for the general public and heath care professionals. It provides a range of resources including information about the latest recommendations by the …

Author: Indian Academy of Pediatrics Advisory Committee on Vaccines and Immunization Practices

Indirect Protection of Adults From Rotavirus by Pediatric Rotavirus Vaccination

Pediatric vaccination has resulted in declines in disease in unvaccinated individuals through decreasing pathogen circulation in the community. About two years after the implementation of pediatric rotavirus vaccination in the United States, …

Author: Anderson EJ, Shippee DB, Weinrobe MH, et al.

Publication date: 2013

The Infant Gut Microbiome Correlates Significantly With Rotavirus Vaccine Response in Rural Ghana

This article, published in the Journal of Infectious Diseases, reports the results of a study examining the differences in intestinal microbiome composition and rotavirus vaccine efficacy in developing-country settings. The authors found that the …

Author: Harris VC, Armah G, Fuentes S, et al.

Publication date: 2016

Infant Rotavirus Vaccination May Provide Indirect Protection to Older Children and Adults in the United States

This article, published in the Journal of Infectious Diseases, reports on a study which found that vaccinating infants in the United States against rotavirus appears to prevent severe disease in older children and adults. The authors examined data …

Author: Lopman BA, Curns AT, Yen C, Parashar UD

Publication date: 2011

An Integrated Approach to Confronting Diarrheal Disease

This briefing paper provides an overview of the tools and interventions involved with an integrated approach to diarrheal disease control, including vaccines, oral rehydration therapy, breastfeeding, and zinc treatment. The document also advocates …

Author: PATH

Publication date: 2011

Integrating Diarrheal Disease and Pneumonia Control

This fact sheet describes PATH's integrated approach to tackling diarrheal disease and pneumonia, two of the leading killers of young children. This approach emphasizes overlapping protection, the scale-up of proven methods, and the development of …

Author: PATH

Publication date: 2013

Intervention Analysis of Introduction of Rotavirus Vaccine on Hospital Admissions Rates Due to Acute Diarrhea

This article, published in Cadernos de Saúde Pública, examined the impact of rotavirus vaccine on hospitalization rates for acute diarrhea in children younger than five years following the 2006 introduction of the vaccine in Brazil. The results …

Author: Masukawa MLT, Moriwaki AM, Uchimura NS, de Souza EM, Uchimura TT

Publication date: 2014

Introducing New Vaccines Into Developing Countries: Obstacles, Opportunities, and Complexities

This commentary, published in Nature Medicine, reviews current trends that may affect whether the most promising of the 350 vaccine candidates under development will eventually be used in programs for the poor in developing countries. It also …

Author: Clemens J, Jodar L

Publication date: 2005

Introduction of Rotavirus Vaccines: Information for Policy Makers, Programme Managers, and Health Workers

This document includes information and guidance to assist policy makers, program managers, and health workers in considering all of the operational preparations that should be included in a rotavirus vaccine introduction plan, once a country has …

Author: World Health Organization

Publication date: 2013

Intussusception After Rotavirus Vaccines Reported to US VAERS, 2006-2012

This article, published in Pediatrics, describes investigators' assessment of intussusception events reported to the Vaccine Adverse Event Reporting System from 2006 through 2012, following the respective introductions of RotaTeq® (Merck & Co., …

Author: Haber P, Patel M, Pan Y, et al.

Publication date: 2013

Intussusception Following Rotavirus Vaccine Administration: Post-Marketing Surveillance in the National Immunization Program in Australia

This article, published in Vaccine, reports that surveillance conducted following routine rotavirus vaccination in Australia did not find an overall increase in intussusception with use of RotaTeq® (Merck & Co., Inc.) and Rotarix® …

Author: Buttery JP, Danchin MH, Lee KJ, et al.

Publication date: 2011

Intussusception Risk after Rotavirus Vaccination in U.S. Infants

This article, published in the New England Journal of Medicine, reports on a study about the potential increased risk of intussusception after rotavirus vaccination with RotaTeq (RV5, a pentavalent vaccine) and Rotarix (RV1, a monovalent vaccine) …

Author: Yih WK, Lieu TA, Kulldorff M, et al.

Publication date: 2014

Intussusception Risk and Health Benefits of Rotavirus Vaccination in Mexico and Brazil

This article, published in The New England Journal of Medicine, assesses the association of the monovalent rotavirus vaccine (RV1) with intussusception after routine immunization of infants in Mexico and Brazil. The authors found that RV1 was …

Author: Patel MM, López-Collada VR, Bulhões MM, et al.

Publication date: 2011

Joint Vaccine Education Resource Center

This website provides resources in the field of immunization, including an extensive selection of peer-reviewed articles from the literature as well as links to valuable resources for scientists, clinicians, and patients focused on the most commonly …

Author: American Journal of Preventative Medicine; Vaccine

Jordan Report: Accelerated Development of Vaccines 2012

This comprehensive report includes expert articles on a variety of vaccine-related topics and updates on vaccine research for specific infectious diseases, such as influenza, malaria, respiratory syncytial virus, and rotavirus.

Author: US National Institute of Allergy and Infectious Diseases

Publication date: 2012

Landscape Analysis: Trends in Vaccine Availability and Novel Vaccine Delivery Technologies: 2008–2025

This landscape analysis identifies trends in the availability of vaccines and novel vaccine delivery technologies that are and will be of relevance to low- and middle-income countries from the present through 2025.

Author: PATH, World Health Organization

Publication date: 2008

Magnitude and Impact of Diarrheal Diseases

Published in The Archives of Medical Research, this article reviews the high costs of diseases of poverty, increasing diarrhea morbidity (despite decreasing mortality), and new emerging evidence for long-term consequences of early childhood …

Author: Guerrant RL, Kosek M, Moore S, et al.

Publication date: 2002

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