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Total results with these characteristics: 38

Disease: Group B Streptococcus (GBS)

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Moving the Needle

This quarterly e-newsletter provides updates from PATH’s Center for Vaccine Innovation and Access on its vaccine development efforts, as well as related supporting work, such as developing human challenge models, building capacity of …

Author: PATH

Neither Antibody to a Group B Streptococcal Conjugate Vaccine nor the Vaccine Itself is Teratogenic in Rabbits

This article, published in Human Vaccines, describes a group B Streptococcus (GBS) type-III capsular polysaccharide (CPS)-tetanus toxoid vaccine lot manufactured under current Good Manufacturing Practice Guidelines. The authors also provide an …

Author: Paoletti LC, Guttormsen H-K, Christian MS, Hoberman AM, McInnes P

Publication date: 2008

Opsonic Specificity of Human Antibody to the Type III Polysaccharide of Group B Streptocccus

This article, published in the Journal of Infectious Diseases, examines the functional significance of vaccine-induced or naturally acquired antibody to the capsular polysaccharide of type III group B Streptococcus. ABSTRACT ONLY. (Learn how users …

Author: Edwards MS, Baker CJ, Kasper DL

Publication date: 1979

Persistence of Functional Antibodies to Group B Streptococcal Capsular Polysaccharides Following Immunization With Glycoconjugate Vaccines

This article, published in Vaccine, evaluates the duration of functional activity of group B streptococcal (GBS) glycoconjugate vaccine-induced capsular polysaccharide (CPS)-specific IgG among healthy adults. The study reveals that opsonophagocytic …

Author: Edwards MS, Lane HJ, Hillier SL, Rench MA, Baker CJ

Publication date: 2012

Potency of Clinical Group B Streptococcal Conjugate Vaccines

This article, published in Vaccine, discusses the potency of clinical group B streptococcal (GBS) capsular polysaccharide-protein conjugate vaccines. It examines liquid versus lyophilized preparations, and the author suggests that lyophilization in …

Author: Paoletti LC

Publication date: 2001

Preventing Bacterial Infections With Pilus-Based Vaccines: The Group B Streptococcus Paradigm

This article, published in the Journal of Infectious Diseases, reports the results of a study that determined whether a vaccine containing a combination of proteins from three pilus types can provide broad protection against group B Streptococcus …

Author: Margarit I, Rinaudo CD, Galeotti CL, et al.

Publication date: 2009

Preventing the Broad Spectrum of Perinatal Morbidity and Mortality Through Group B Streptococcal Vaccination

This article, published in Vaccine, presents the specific pregnancy-associated and neonatal conditions attributable, in part, to group B Streptococcus (GBS) in high- and lower-income countries. The authors provide a rationale for implementation of …

Author: Edwards MS, Gonik B

Publication date: 2013

Prevention of Group B Streptococcal Disease in the First 3 Months of Life: Would Routine Maternal Immunization During Pregnancy Be Cost-Effective?

This article, published in Vaccine, reports the results of a study that evaluated the potential cost-effectiveness of a trivalent group B streptococcal (GBS) vaccine candidate with a decision-analytic model. The authors found that the addition of a …

Author: Oster G, Edelsberg J, Hennegan K, et al.

Publication date: 2014

Protect Your Baby From Group B Strep

This podcast, narrated by pediatrician Tarayn Fairlie, discusses group B Streptococcus (GBS) in pregnant women, the serious effects it can have on newborns, how to find out if you have GBS bacteria in your body, and ways to prevent spreading it to …

Author: US Centers for Disease Control and Prevention

Publication date: 2011

Protecting Mother and Baby From Infectious Diseases

This fact sheet describes PATH’s work in maternal immunization—an approach of vaccinating during pregnancy to protect the mother and baby. It covers work across vaccine projects targeting respiratory syncytial virus, influenza, group B …

Author: PATH

Publication date: 2017

Quantitative Determination of Antibodies to Type III Group B Streptococcal Polysaccharide

This article, published in the Journal of Infectious Diseases, reports the results of a study using an enzyme-linked immunosorbent assay (ELISA) to measure type III group B streptocci (GBS) antibodies. The authors found that the ELISA was able to …

Author: Guttormsen H-K, Baker CJ, Edwards MS, Paoletti LC, Kasper DL

Publication date: 1996

Recombinant Group B Streptococcus Beta C Protein and a Variant With the Deletion of its Immunoglobulin A-Binding Site Are Protective Mouse Maternal Vaccines and Effective Carriers in Conjugate Vaccines

This article, published in Infection and Immunity, reports the results of a study in mice that examined immunogenicity and protective efficacy of a recombinant group B Streptococcus beta C protein (rBCP), an rBCP modified to eliminate its …

Author: Yang H-H, Madoff LC, Guttormsen H-K, Liu Y-D, Paoletti LC

Publication date: 2007

Review on the Association of Group B Streptococcus Capsular Antibody and Protection Against Invasive Disease in Infants

Establishing sero-correlates of protection against invasive group B Streptococcus (GBS) disease in infants could expedite the licensure pathway of polysaccharide-protein conjugate vaccines. This article, published in Expert Review of Vaccines, …

Author: Dangor Z, Kwatra G, Izu A, Lala SG, Madhi SA

Publication date: 2015

Safety and Immunogenicity of a Bivalent Group B Streptococcal Conjugate Vaccine for Serotypes II and III

This article, published in the Journal of Infectious Diseases, reports the results of a study to determine whether two monovalent group B Streptococcus (GBS) serotype II or III capsular polysaccharide-tetanus toxoid conjugate vaccines combined in a …

Author: Baker CJ, Rench MA, Fernandez M, Paoletti LC, Kasper DL, Edwards MS

Publication date: 2003

Safety and Immunogenicity of Capsular Polysaccharide—Tetanus Toxoid Conjugate Vaccines for Group B Streptococcal Types Ia and Ib

This article, published in the Journal of Infectious Diseases, reports the results of a study to evaluate the safety, immounogenicity, and optimal dose in healthy women of group B Streptococcus (GBS) type Ia- and type Ib-tetanus toxoid (TT) …

Author: Baker CJ, Paoletti LC, Wessels MR, et al.

Publication date: 1999

The Spectrum of Perinatal Group B Streptococcal Disease

This article, published in Vaccine, examines four decades' worth of understanding about group B Streptococcus (GBS) global disease burden. This review highglights, in historical context, the recognition of GBS as a human pathogen, epidemiologic …

Author: Baker CJ

Publication date: 2013

An Update on Vaccination Against Group B Streptococcus

This article, published in Expert Review of Vaccines, examines the vaccine development pipeline for group B Streptococcus (GBS). The authors note that a number of candidates have the potential to be successful, but that there are issues still to be …

Author: Heath PT

Publication date: 2011

WHO Consultation on Group B Streptococcus Vaccine Development: Report From a Meeting Held on 27-28 April 2016

This article, published in Vaccine, reports the outcome of a World Health Organization technical consultation that considered development pathways for group B Streptococcus (GBS) vaccines. The meeting discussed numerous topics, including disease …

Author: Kobayashi M, Schrag SJ, Alderson MR, et al.

Publication date: 2016

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