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Disease: Typhoid

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Safety and Immunogenicity of a Vi Polysaccharide–Tetanus Toxoid Conjugate Vaccine (Typbar-TCV) in Healthy Infants, Children, and Adults in Typhoid Endemic Areas: A Multicenter, 2-Cohort, Open-Label, Double-Blind, Randomized Controlled Phase 3 Study

This article, published in Clinical Infectious Diseases, reports the results of a study examining the safety and efficacy of a typhoid conjugate vaccine in people aged 6 months to 24 years conducted at eight trial sites in India. The results showed …

Author: Mohan VK, Varanasi V, Singh A, et al.

Publication date: 2015

Social and Economic Burden Associated With Typhoid Fever in Kathmandu and Surrounding Areas: A Qualitative Study

Typhoid fever is highly endemic in Nepal, but data is limited regarding the social and economic burdens of the disease on affected households or challenges faced at the local level in terms of disease diagnosis, treatment, and prevention. This …

Author: Kaljee LM, Pach A, Garrett D, Bajracharya D, Karki K, Khan I

Publication date: 2017

State of the World's Vaccines and Immunization, Third Edition

This report focuses on the major developments in vaccines and immunization since 2000. Part 1 examines the impact of immunization on efforts to meet the Millennium Development Goals. It looks at the development and use of vaccines and the …

Author: World Health Organization, United Nations Children's Fund, World Bank

Publication date: 2009


This web page provides information and links to resources about typhoid disease and vaccines, including World Health Organization position papers, prequalified vaccines, and technical resources.

Author: World Health Organization

Typhoid Fever

This web page provides information and resources on typhoid. Topics include general information about the disease, symptoms and treatment, prevention methods, vaccination, and disease surveillance.

Author: US Centers for Disease Control and Prevention

Typhoid Fever and Paratyphoid Fever: Systematic Review to Estimate Global Morbidity and Mortality for 2010

This article, published in the Journal of Global Health, summarizes the findings of a systematic literature review of population-based studies and country disease surveillance reports with typhoid and paratyphoid fever incidence data published …

Author: Buckle GC, Fischer Walker CL, Black RE

Publication date: 2012

Typhoid Fever Surveillance in Africa Program (TSAP)

This supplement issue of Clinical Infectious Diseases provides a collection of articles about typhoid disease burden in Africa. Previous research has focused on typhoid's burden in Asia, and little was known about the burden in Africa. The …

Author: Marks F, ed.

Publication date: 2016

Typhoid Fever Vaccination Strategies

This article, published in Vaccine, reviews experiences with various vaccination strategies using the currently availabile typhoid vaccines—injectable Vi polysaccharide vaccine (ViPS), oral Ty21a vaccine, and injectable typhoid conjugate vaccine …

Author: Date KA, Bentsi-Enchill A, Marks F, Fox K

Publication date: 2015

Typhoid in Africa and Vaccine Deployment

This article, published in The Lancet Global Health, summarizes the findings of the Typhoid Surveillance in Africa Programme (TSAP), current limitations with diagnostics and surveillance, and the need for new diagnostics and vaccines in the face of …

Author: Dougan G

Publication date: 2017

The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine Effectiveness Study Designs: Accelerating the Introduction of Typhoid Conjugate Vaccines and Reducing the Global Burden of Enteric Fever. Report From a Meeting Held on 26–27 October 2016, Oxford, UK

This article, published in Vaccine, summarizes the results of a meeting held in October 2016 to initiate planning of typhoid conjugate vaccine (TCV) effectiveness studies that will provide the data required by policymakers and stakeholders to …

Author: Meiring JE, Gibani M, TyVAC Consortium Meeting Group

Publication date: 2017

Typhoid Vaccine Introduction: An Evidence-Based Pilot Implementation Project in Nepal and Pakistan

This article, published in Vaccine, reports the results of a pilot program to assess the feasibility of school-based typhoid vaccination in two districts in Kathmandu, Nepal, and two towns in Karachi, Pakistan. Vaccination campaigns were conducted …

Author: Khan MI, Pach A 3rd, Khan GM, et al.

Publication date: 2015

Typhoid Vaccines: WHO Position Paper

This report, published in the Weekly Epidemiological Record, provides the World Health Organization’s current recommendation on the use of typhoid vaccines in a global context. It summarizes essential background information on typhoid disease and …

Author: World Health Organization

Publication date: 2008

The Unrecognized Burden of Typhoid Fever

This article, published in Expert Review of Vaccines, provides an overview of the gaps in current estimates of typhoid fever disease burden and offers suggestions for addressing them so that affected communities can receive the full potential of …

Author: Obaro SK, Iroh Tam PY, Mintz ED

Publication date: 2017

Vaccine Position Papers

This web page provides links to all of the World Health Organization's position papers on specific vaccines. In addition to linking to these resources in English, it also provides links to translations of the papers into other languages, as well as …

Author: World Health Organization

Vaccines for Preventing Typhoid Fever

This article, published in the Cochrane Database of Systematic Reviews, evaluates the safety and efficacy of vaccines used to prevent typhoid. The review includes information on the two licensed and globally available typhoid vaccines—the oral …

Author: Anwar E, Goldberg E, Fraser A, Acosta CJ, Paul M, Leibovici L

Publication date: 2014

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