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Total results with these characteristics: 68

Disease: Respiratory syncytial virus (RSV)

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Prevention of Serious Respiratory Syncytial Virus-Related Illness. II: Immunoprophylaxis

This article, published in Advances in Therapy, reviews the development and use of palivizumab, the only drug approved for the prevention of respiratory syncytial virus (RSV) lower respiratory tract disease. Palivizumab is a monoclonal antibody that …

Author: Groothuis JR, Hoopes JM, Hemming VG

Publication date: 2011

Protecting Aluminum-Adjuvanted Vaccines From Freeze Damage

This fact sheet describes how PATH developed a low-cost and straightforward technology for protecting aluminum-adjuvanted liquid vaccines from the irreversible damage that results from freezing. Many current vaccines of importance to global health …

Author: PATH

Publication date: 2012

Protecting Mother and Baby From Infectious Diseases

This fact sheet describes PATH’s work in maternal immunization—an approach of vaccinating during pregnancy to protect the mother and baby. It covers work across vaccine projects targeting respiratory syncytial virus, influenza, group B …

Author: PATH

Publication date: 2017

Quantifying Maternally Derived Respiratory Syncytial Virus Specific Neutralising Antibodies in a Birth Cohort From Coastal Kenya

This article, published in Vaccine, reports on the characteristics of respiratory syncytial virus (RSV) neutralizing antibodies in a birth cohort in Kilifi, Kenya, which provides important data for maternal RSV vaccine development. Results showed …

Author: Nyiro JU, Sande C, Mutunga M, et al.

Publication date: 2015

A Randomized, Blinded, Controlled, Dose-Ranging Study of a Respiratory Syncytial Virus Recombinant Fusion (F) Nanoparticle Vaccine in Healthy Women of Childbearing Age

This article, published in the Journal of Infectious Diseases, reports the results of a study to evaluate the safety and immunogenicity of a recombinant respiratory syncytial virus (RSV) vaccine candidate for maternal immunization. The vaccine was …

Author: Glenn GM, Fries LF, Thomas DN, et al.

Publication date: 2016

Respiratory Syncytial Virus: Infection, Detection, and New Options for Prevention and Treatment

This article, published in Clinical Microbiology Reviews, discusses developments in the understanding of respiratory syncytial virus (RSV) replication, pathogenesis, diagnostics, and therapeutics. It reconciles the body of information on RSV and …

Author: Griffiths C, Drews SJ, Marchant DJ

Publication date: 2017

Respiratory Syncytial Virus Infection in Infants in Rural Nepal

Respiratory syncytial virus (RSV) is a leading cause of infant mortality worldwide, but the risk of RSV is not well-characterized in resource-limited settings. This article, published in Journal of Infection, reports the results of a study that …

Author: Chu HY, Katz J, Tielsch J, et al.

Publication date: 2016

Respiratory Syncytial Virus Infection (RSV)

This web page provides a wide spectrum of information about respiratory syncytial virus (RSV) in the United States. It offers a general overview of the disease as well as clinical, research, and surveillance information. Specific topics include, …

Author: US Centers for Disease Control and Prevention

Respiratory Syncytial Virus Transplacental Antibody Transfer and Kinetics in Mother-Infant Pairs in Bangladesh

This article, published in The Journal of Infectious Diseases, summarizes a serological study conducted in Dhaka, Bangladesh that documented efficient transplacental transfer of respiratory syncytial virus (RSV)-specific antibody from mother to the …

Author: Chu HY, Steinhoff MC, Magaret A, et al.

Publication date: 2014

Risk Factors for Respiratory Syncytial Virus Associated With Acute Lower Respiratory Infection in Children Under Five Years: Systematic Review and Meta-Analysis

This article, published in the Journal of Global Health, reports the results of a study that identified risk factors for respiratory syncytial virus (RSV)-associated acute lower respiratory infection (ALRI) in young children. The study presents a …

Author: Shi T, Balsells E, Wastnedge E, et al.

Publication date: 2015

RSV Vaccine and mAb Snapshot

This slide provides a snapshot of the respiratory syncytial virus (RSV) vaccine and monoclonal antibody (mAb) technology landscape, in the effort to track the development of RSV vaccine and mAb candidates and provide a summary of the various such …

Author: PATH

Publication date: 2017

RSV Vaccine Research and Development Technology Roadmap

This report provides a strategic framework for respiratory syncytial virus (RSV) vaccine development. It identifies priority activities in four key categories—research, vaccine development, key capacities, and policy and delivery—that need to be …

Author: World Health Organization

Publication date: 2017

RSV Vaccine Use – The Missing Data

This article, published in Expert Review of Vaccines, explains the need for more data and knowledge on respiratory syncytial virus (RSV) epidemiology in different settings and age groups, as well as virus transmission and healthcare costs of the …

Author: Drysdale SB, Sande CJ, Green CA, Pollard AJ

Publication date: 2016

Soluble Respiratory Syncytial Virus Fusion Protein in the Fully Cleaved, Pretriggered State is Triggered by Exposure to Low-Molarity Buffer

This article, published by the Journal of Virology, discusses research conducted to study the triggering mechanism of a soluble respiratory syncytial virus fusion protein. ABSTRACT ONLY. (Learn how users in developing countries can gain free access …

Author: Chaiwatpongsakorn S, Epand RF, Collins PL, Epand RM, Peeples ME

Publication date: 2011

Strategic Priorities for Respiratory Syncytial Virus (RSV) Vaccine Development

This review article, published in Vaccine, examines the clinical and epidemiological features of respiratory syncytial virus (RSV), highlights challenges and opportunities for RSV vaccine development, and identifies priority areas for future …

Author: Anderson LJ, Dormitzer PR, Nokes DJ, Rappuoli R, Roca A, Graham BS

Publication date: 2013

Strengthening Maternal Immunisation to Improve the Health of Mothers and Infants

Innovative approaches to maternal immunization have the potential to decrease serious morbidity and mortality not only in the mother, but also in the baby who is not yet able to immunologically respond to most vaccines. This article, published in …

Author: Abramson JS, Mason E

Publication date: 2016

Structural Basis for Immunization With Postfusion Respiratory Syncytial Virus Fusion F Glycoprotein (RSV F) to Elicit High Neutralizing Antibody Titers

Respiratory syncytial virus (RSV) vaccine candidates based on a chief RSV neutralization antigen, the fusion (F) glycoprotein, have foundered due to problems with stability, purity, reproducibility, and potency. The authors of this article, …

Author: Swanson KA, Settembre EC, Shaw CA, et al.

Publication date: 2011

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

This article, published in Science, describes research to characterize the respiratory syncytial virus (RSV) fusion glycoprotein prefusion conformation, which is the target of most RSV-neturalizing activity in human sera. ABSTRACT ONLY: (Learn how …

Author: McLellan JS, Chen M, Leung S, et al

Publication date: 2013

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

This article, published in Science, describes research to engineer a respiratory synctial virus (RSV) viral antigen that focuses on antigenic site ø, a metastable site specific to the prefusion state of the RSV fusion glycoprotein. ABSTRACT ONLY. …

Author: McLellan JS, Chen M, Joyce MG, et al.

Publication date: 2013

Surveillance for Respiratory Syncytial Virus in CDC's Global Disease Detection Network: Epidemiology, Disease Burden and Clinical Characteristics

This supplement to The Journal of Infectious Diseases features articles on respiratory syncytial virus (RSV) surveillance data through the US Centers for Disease Control and Prevention's (CDC's) Global Disease Detection Network . The 12 articles …

Author: Iwane MK, Garnon EC, Gerber SI, eds.

Publication date: 2013

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