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Disease: Rotavirus

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Disease Control Priorities, Third Edition: Volume 2. Reproductive, Maternal, Newborn, and Child Health

This book focuses on maternal conditions, childhood illness, and malnutrition. Specifically, the chapters address acute illness and undernutrition in children, principally under age five. Of particular interest may be chapters 9, 10, and 19, which …

Author: Black RE, Laxminarayan R, Temmerman M, Walker N, eds.

Publication date: 2016

Diseases and the Vaccines That Prevent Them: For Parents of Infants and Young Children (Birth Through Age 6)

This series of fact sheets describes symptoms of infection as well as the benefits and risk of vaccination for 14 diseases, specifically for vaccines recommended for children from birth through the age of six years. Each fact sheet include an …

Author: US Centers for Disease Control and Prevention

Distribution of Rotavirus Genotypes in Europe, 2004-2005: The REVEAL Study

Rotavirus genotypes were identified in several European countries using ELISA tests, and investigators determined that G1–G4 and G9 genotypes were responsible for the majority of cases. Citing these results, the authors suggest that rotavirus …

Author: Van Damme P, Giaquinto C, Maxwell M, Todd P, Van der Wielen M

Publication date: 2007

Distributional Impact of Rotavirus Vaccination in 25 GAVI Countries: Estimating Disparities in Benefits and Cost-Effectiveness

This article, published in Vaccine, reports on an analysis that combines the results of a country-level model of rotavirus vaccination published elsewhere with data from Demographic and Health Surveys on within-country patterns of vaccine coverage …

Author: Rheingans R, Atherly D, Anderson J

Publication date: 2012

A Dose-Escalation Safety and Immunogenicity Study of Live Attenuated Oral Rotavirus Vaccine 116E in Infants: A Randomized, Double-Blind, Placebo-Controlled Trial

This study, published in the Journal of Infectious Diseases, tested the neonatal rotavirus candidate vaccine 116E in a double-blind, placebo-controlled dose-escalation trial in India. Two doses of the Vero cell-adapted vaccine were evaluated in …

Author: Bhandari N, Sharma P, Taneja S, et al.

Publication date: 2009

Duration of Protection of Pentavalent Rotavirus Vaccination in Nicaragua

This article, published in Pediatrics, summarizes a case-control study conducted at four hospitals in Nicaragua to evaluate the duration of protection after rotavirus vaccination among eligible infants. The pentavalent rotavirus vaccine protected …

Author: Patel M, Pedreira C, De Oliveira LH, et al.

Publication date: 2012

Early Impact of Rotavirus Vaccination in Children Less Than Five Years of Age in Mozambique

This article, published in Vaccine, describes a study that aimed to evaluate the early impact of rotavirus vaccine in reducing all-cause diarrhea and rotavirus-specific hospitalizations among children under five years of age in Mozambique following …

Author: de Deus N, Chilaule JJ, Cassocera M, et al.

Publication date: 2017

The Economic Burden Attributable to a Child’s Inpatient Admission for Diarrheal Disease in Rwanda

This article, published in PLoS ONE, reports the results of a study that aimed to estimate the economic burden attributable to hospitalization for diarrhea among children less than five years old in Rwanda. The authors also compared the economic …

Author: Ngabo F, Mvundura M, Gazley L, et al.

Publication date: 2016

Economic Costs of Rotavirus Gastroenteritis and Cost-Effectiveness of Vaccination in Developing Countries

This article, published in The Journal of Infectious Diseases, evaluated the economic burden of rotavirus and the cost-effectiveness of vaccination from the health care perspective. The authors found that rotavirus vaccination would annually prevent …

Author: Rheingans RD, Antil L, Dreibelbis R, Podewils LJ, Bresee JS, Parashar UD

Publication date: 2009

Economic Evaluations of Rotavirus Immunization for Developing Countries: A Review of the Literature

This article, published in Expert Review of Vaccines, analyzes the cost-effectiveness of universal rotavirus immunization in developing countries. The authors identified and evaluated 15 cost-effectiveness studies conducted in the developing world. …

Author: Tu HA, Woerdenbag HJ, Kane S, Rozenbaum MH, Li SC, Postma MJ

Publication date: 2011

Economic Impact of a Rotavirus Vaccination Program in Mexico

This article, published in the Pan American Journal of Public Health, examines a national rotavirus vaccination program in Mexico and evaluates its costs and benefits. The article concludes that the program would be highly cost-effective and …

Author: Constenla D, Velázquez FR, Rheingans RD, Antil L, Cervantes Y

Publication date: 2009

The Economic Impact of Childhood Acute Gastroenteritis on Malawian Families and the Healthcare System

This article, published in BMJ Open, reports on a study that found significant financial burden from childhood diarrheal disease to the healthcare system and to households in Malawi. The latter face the risk of consequent impoverishment, as the …

Author: Hendrix N, Bar-Zeev N, Atherly D, et al.

Publication date: 2017

Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants

This article, published in The New England Journal of Medicine, discusses a study on the efficacy of rotavirus vaccine in Africa. Results showed 30.2 percent efficacy against all-cause severe gastroenteritis. The study concluded that rotavirus …

Author: Madhi SA, Cunliffe NA, Steele D, et al.

Publication date: 2010

Effect of Pentavalent Rotavirus Vaccine Introduction on Hospital Admissions for Diarrhoea and Rotavirus in Children in Rwanda: A Time-Series Analysis

This article, published in The Lancet Global Health, reports on the results of a time-series analysis that examined hospital admissions of children under five years of age due to diarrhea in Rwanda from 2009 to 2014. The authors compared hospital …

Author: Ngabo F, Tate JE, Gatera M, et al.

Publication date: 2016

Effect of Rotavirus Vaccination on Death From Childhood Diarrhea in Mexico

This article, published in The New England Journal of Medicine, discusses a study on the effectiveness of rotavirus vaccine in Mexico. The study examined the impact of vaccination on diarrheal deaths in Mexican children between 2008 and 2009 …

Author: Richardson V, Hernandez-Pichardo J, Quintanar-Solares M, et al.

Publication date: 2010

Effect of Rotavirus Vaccine on Diarrhea Mortality in Different Socioeconomic Regions of Mexico

This article, published in Pediatrics, concludes that after the 2007 introduction of rotavirus vaccine in Mexico, marked and sustained declines in diarrhea deaths were seen among children in all regions of the country, including in the least …

Author: Gastañaduy PA, Sánchez-Uribe E, Esparza-Aguilar M, et al.

Publication date: 2013

Effectiveness of a Live Oral Human Rotavirus Vaccine After Programmatic Introduction in Bangladesh: A Cluster-Randomized Trial

This article, published in PLoS Medicine, evaluated the efficacy of the two-dose human rotavirus vaccine program on the schedule currently recommended by the World Health Organization in a low-resource population in Bangladesh, the first such …

Author: Zaman K, Sack DA, Neuzil KM, et al.

Publication date: 2017

Effectiveness of a Monovalent Rotavirus Vaccine in Infants in Malawi After Programmatic Roll-Out: An Observational and Case-Control Study

This article, published in The Lancet Infectious Diseases, reports on a study to evaluate the effectiveness of a monovalent rotavirus vaccine in infants in Malawi. The authors found that the vaccine was 64 percent effective in preventing …

Author: Bar-Zeev N, Kapanda L, Tate JE, et al.

Publication date: 2015

Effectiveness of Monovalent Human Rotavirus Vaccine Against Admission to Hospital for Acute Rotavirus Diarrhoea in South African Children: A Case-Control Study

This study, published in The Lancet Infectious Diseases, examined the effectiveness of rotavirus vaccine in an African setting with a high prevalence of HIV infection. The findings showed that human rotavirus vaccine provided sustained protection …

Author: Groome MJ, Page N, Cortese MM, et al.

Publication date: 2014

Effectiveness of Monovalent Rotavirus Vaccine in Bolivia: Case-Control Study

This article, published in BMJ, reports on a study that evaluated the effectiveness of two doses of a monovalent rotavirus vaccine against hospital admission for rotavirus at six hospitals in Bolivia, between March 2010 and June 2011. Results show …

Author: Patel MM, Patzi M, Pastor D, et al.

Publication date: 2013

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