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Vaccine Discovery and Translation of New Vaccine Technology

An unprecedented increase in new vaccine development has occurred over the past three decades. This article, published in The Lancet, discusses new methods of discovery, such as reverse vaccinology, structural biology, and systems biology, which promise new vaccines for different diseases and efficient development pathways for these vaccines. The authors argue that the success of these new approaches will depend on effective implementation of vaccination programs, creative thinking on the part of manufacturers and regulators as to how best to ensure that safe and effective vaccines are available in a timely manner, and improvement of public awareness about the benefits and risks of new vaccines in a way that encourages confidence in vaccines.

Author: Rappuoli R, Black S, Lambert PH

Published: 2011

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Citation: Rappuoli R, Black S, Lambert PH. Vaccine Discovery and Translation of New Vaccine Technology. The Lancet. 2011;378(9788):360-368.

Resource types: Peer-reviewed journal

Diseases/vaccines: Not disease/vaccine specific

Topics: Advocacy and communications, Introduction and service delivery, Vaccine safety and performance

Regions: Global