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Influenza Vaccination of Pregnant Women and Protection of Their Infants

This article, published in the New England Journal of Medicine, presents results from two double-blind, randomized, placebo-controlled trials of trivalent inactivated influenza vaccine (IIV3) in South Africa during 2011 in pregnant women infected with HIV and during 2011 and 2012 in pregnant women who were not infected. The research contributes new data on the efficacy of vaccination against confirmed influenza in pregnant women with and without HIV infection and protection of their infants. The authors found IIV3 to be immunogenic in HIV-uninfected and HIV-infected pregnant women and to provide partial protection against confirmed influenza in both groups of women and in infants who were not exposed to HIV. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: Madhi SA, Cutland CL, Kuwanda L, et al.

Published: 2014

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Citation: Madhi SA, Cutland CL, Kuwanda L, et al. Influenza Vaccination of Pregnant Women and Protection of Their Infants. New England Journal of Medicine. 2014;371:918-931. 

Resource types: Peer-reviewed journal

Diseases/vaccines: Influenza

Topics: Vaccine safety and performance, Disease/vaccine specific information

Regions: Africa