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Combination Vaccines Against Diarrheal Diseases

This article, published in Human Vaccines & Immunotherapeutics, outlines the need for the development of affordable and effective combination vaccines against diarrheal diseases. Despite the well-documented global burden of diarrheal diseases, currently there are no combination diarrheal vaccines, only licensed vaccines for rotavirus and cholera, and Salmonella typhi-based vaccines for typhoid fever. The authors argue that combination pediatric vaccines have proven to be an effective tool in limiting or eradicating communicable childhood diseases, and the current landscape of diarrheal vaccine candidates indicate that there are now several in active development that offer options for potential testing of combinations for the pathogens responsible for the heaviest disease burden.

Author: Venkatesan MM, Van de Verg LL

Published: 2015

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Citation: Venkatesan MM, Van de Verg LL. Combination Vaccines Against Diarrheal Diseases. Human Vaccines & Immunotherapeutics. 2015;11(6):1434-1448.

Resource types: Peer-reviewed journal

Diseases/vaccines: Shigellosis and enterotoxigenic Escherichia coli (ETEC), Rotavirus, Typhoid

Topics: Disease burden and surveillance, Disease/vaccine specific information

Regions: Global