Assessment of Pfs25 Expressed from Multiple Soluble Expression Platforms for Use as Transmission-Blocking Vaccine Candidates
Transmission-blocking vaccines (TBVs) have become a focus of strategies to control and eventually eliminate malaria as they target the entry of sexual stage into the Anopheles stephensi mosquito thereby preventing transmission, an essential component of the parasite life cycle. Such vaccines are envisioned as complements to vaccines that target human infection, such as RTS,S as well as drug treatment, and vector control strategies. This article, published in Malaria Journal, explores the Pfs25 protein, which has been identified as a promising TBV target in research or early stage development.
Author: Lee S-M, Wu C-K, Plieskatt J, et al.
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Citation: Lee S-M, Wu C-K, Plieskatt J, et al. Assessment of Pfs25 Expressed From Multiple Soluble Expression Platforms for Use as Transmission-Blocking Vaccine Candidates. Malaria Journal. 2016;15:405.
Resource types: Peer-reviewed journal