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Vaccines for Preventing Typhoid Fever

This article, published in the Cochrane Database of Systematic Reviews, evaluates the safety and efficacy of vaccines used to prevent typhoid. The review includes information on the two licensed and globally available typhoid vaccines—the oral Ty21a vaccine and the injected Vi polysaccharide vaccine—as well as a typhoid conjugate vaccine (TCV) candidate in development. The authors found that the Ty21a and Vi polysaccharide vaccines are safe and effective in reducing typhoid fever and the new, unlicensed TCV reviewed is as efficacious and may confer longer immunity.

Author: Anwar E, Goldberg E, Fraser A, Acosta CJ, Paul M, Leibovici L

Published: 2014

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Citation: Anwar E, Goldberg E, Fraser A, Acosta CJ, Paul M, Leibovici L. Vaccines for Preventing Typhoid Fever. Cochrane Database of Systematic Reviews. 2014;2(1).

Resource types: Peer-reviewed journal

Diseases/vaccines: Typhoid

Topics: Vaccine safety and performance, Disease/vaccine specific information

Regions: Global