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Burden of Disease and Circulating Serotypes of Rotavirus Infection in Sub-Saharan Africa: Systematic Review and Meta-analysis

To assess the potential impact of rotavirus vaccines in sub-Saharan Africa, researchers reviewed recent published data on rotavirus burden among children aged five years old and circulating serotypes in sub-Saharan Africa. Though many countries lack information on rotavirus epidemiology, the authors estimate that 300,000 children die of rotavirus in the region each year. They emphasize that documenting the burden of disease and circulating strains is essential to assess the vaccine effectiveness and impact. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: Sanchez-Padilla E, Grais RF, Guerin PJ, et al.

Published: 2009

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Citation: Sanchez-Padilla E, Grais RF, Guerin PJ, et al. Burden of disease and circulating serotypes of rotavirus infection in sub-Saharan Africa: systematic review and meta-analysis. Lancet Infectious Diseases. 2009;9(9):567-576.

Resource types: Peer-reviewed journal

Diseases/vaccines: Rotavirus

Topics: Disease burden and surveillance

Regions: Africa