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Total results with these characteristics: 410

Topic: Vaccine safety and performance

Page 5 of 21
Efficacy of High-Dose versus Standard-Dose Influenza Vaccine in Older Adults

This article, published in the New England Journal of Medicine, details a study to evaluate if a high dose (60 µg of hemagglutinin per strain) of trivalent, inactivated influenza vaccine (IIV3) improves protection against laboratory-confirmed …

Author: DiazGranados CA, Dunning AJ, Kimmel M, et al.

Publication date: 2014

Efficacy of Human Rotavirus Vaccine Against Rotavirus Gastroenteritis During the First 2 Years of Life in European Infants: Randomised, Double-Blind Controlled Study

This article, published in The Lancet, presents data that show high efficacy for GSK's Rotarix® administered with routine vaccines. Over two seasons, Rotarix® demonstrated 90 percent efficacy against severe rotavirus among European children and …

Author: Vesikari T, Karvonen A, Prymula R, et al.

Publication date: 2007

Efficacy of the HPV-16/18 AS04-Adjuvanted Vaccine Against Low-Risk HPV Types (PATRICIA Randomized Trial): An Unexpected Observation

This article, published in the Journal of Infectious Diseases, reports on a post hoc analysis of the Phase 3 PATRICIA (PApilloma TRIal against Cancer In young Adults) trial that was performed to ascertain whether protection against low-risk human …

Author: Szarewski A, Skinner SR, Garland SM, et al.

Publication date: 2013

Efficacy, Safety, and Immunogenicity of the Human Papillomavirus 16/18 AS04-Adjuvanted Vaccine in Women Older Than 25 Years: 4-Year Interim Follow-Up of the Phase 3, Double-Blind, Randomised Controlled VIVIANE Study

This article, published in The Lancet, discusses the results of an efficacy, safety, and immunogenicity study of the human papillomavirus (HPV) 16/18 vaccine in adult women. The results showed that in women older than 25 years, the HPV 16/18 vaccine …

Author: Skinner SR, Szarewski A, Romanowski B, et al.

Publication date: 2014

Efficacy, Safety, and Immunogenicity of the Human Papillomavirus 16/18 AS04-Adjuvanted Vaccine in Women Older Than 25 Years: 7-Year Follow-Up of the Phase 3, Double-Blind, Randomized Controlled VIVIANE Study

Although the risk of human papillomavirus (HPV) infection is greatest in young women, women older than 25 years of age remain at risk. This article, published in The Lancet Infectious Diseases, reports the results of a 7-year follow-up study of the …

Author: Wheeler CM, Skinner SR, Del Rosario-Raymundo MR, et al.

Publication date: 2016

Estimating the Full Public Health Value of Vaccination

This conference report, published in Vaccine, builds upon a discussion in the public health community on how to assess and incorporate, in addition to safety and measures of protective efficacy, the full public health value (FPHV) of preventive …

Author: Gessner BD, Kaslow D, Louis J, et al.

Publication date: 2017

Estimation of the Potential Overall Impact of Human Papillomavirus Vaccination on Cervical Cancer Cases and Deaths

This article, published in Vaccine, reports on a study that aimed to estimate the potential real-life impact of the AS04-adjuvanted HPV-16/18 vaccine on cervical cancer cases and deaths at the country level. The authors found that HPV vaccination …

Author: Van Kriekinge G, Castellsagué X, Cibula D, Demarteau N

Publication date: 2014

Evaluating the Potential Risks and Benefits of Infant Rotavirus Vaccination in England

This article, published in Vaccine, reports on a risk-benefit analysis of rotavirus vaccination that compared potential vaccine-related risks with estimated vaccine benefits in the 2012 birth cohort in England. The authors estimate that rotavirus …

Author: Clark A, Jit M, Andrews N, Atchison C, Edmunds WJ, Sanderson C

Publication date: 2014

Evaluation of Influenza Vaccine Effectiveness: A Guide to the Design and Interpretation of Observational Studies

This report provides guidance on the evaluation of influenza vaccine effectiveness (VE) studies, primarily for researchers and public health scientsts. It is divided into nine sections and illustrates critical considerations in the design, analysis, …

Author: World Health Organization

Publication date: 2017

Evaluation of Intussusception After Monovalent Rotavirus Vaccination in Africa

This article, published in the New England Journal of Medicine, reports the results of a study to assess the association between monovalent rotavirus vaccine and intussusception in lower-income sub-Saharan African countries. The authors analyzed …

Author: Tate JE, Mwenda JM, Armah G, et al.

Publication date: 2018

Evaluation of the Safety, Tolerability, and Immunogenicity of an Oral, Inactivated Whole-Cell Shigella flexneri 2a Vaccine in Healthy Adult Subjects

This article, published in Clinical and Vaccine Immunology, reports the results of a Phase 1 clinical study that evaluated the safety and immunogenicity of a Shigella vaccine candidate. The results showed that the vaccine was well tolerated and …

Author: Chakraborty S, Harro C, DeNearing B, et al.

Publication date: 2016

Evaluation of Two Lead Malaria Transmission-Blocking Vaccine Candidate Antibodies in Natural Parasite-Vector Combinations

This article, published in Scientific Reports, reports the results of a study to assess the efficacy of two lead transmission-blocking vaccine candidates targeting Pfs25 and Pfs230 antigens to prevent transmission of naturally occuring parasites to …

Author: Bompard A, Da DF, Yerbanga RS, et al.

Publication date: 2017

Evaluation of Vaccines Against Enteric Infections: A Clinical and Public Health Research Agenda for Developing Countries

This article, from the Philosophical Transactions of the Royal Society B, provides a review of the enteric vaccines currently available and their lack of use in developing countries. The author purports that the reasons for this are multiple and …

Author: Clemens J

Publication date: 2011

The Evidence Base for Pneumococcal Conjugate Vaccines (PCVs): Data for Decision-Making Around PCV Use in Childhood

This report provides the latest information on pneumococcal conjugate vaccines (PCV) and their use in routine immunization programs around the world. It includes key background on the burden of pneumococcal disease in children and the impact of PCVs …

Author: International Vaccine Access Center

Publication date: 2017

The Final Phase of Polio Eradication and Endgame Strategies for the Post-Eradication Era

This supplemental issue of the Journal of Infectious Diseases features over 60 original research articles that focus on six aspects of polio eradication—acceleration of eradication; regional and country experiences; epidemiologic, virologic, and …

Author: Cochi SL, Jafari HS, Armstrong GL, et al., eds.

Publication date: 2014

First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

A malaria vaccine, deployed in combination with current malaria-control tools, could play an important role in future control and eventual elimination of malaria in Africa. This article, published in the New England Journal of Medicine, reports the …

Author: The RTS,S Clinical Trials Partnership

Publication date: 2011

Flu Information: Your Guide to Online Flu Resources

This website provides resources to help healthcare professionals communicate about influenza. It includes pandemic and seasonal influenza communications resource libraries, containing materials created by public health agencies across the United …

Author: National Public Health Information Coalition

For Parents: Vaccines for Your Children

This web page offers a variety of resources for parents seeking to learn more about childhood immunizations and the diseases that can be prevented with vaccines. Topics include age-specific vaccine information, immunization records and requirements, …

Author: US Centers for Disease Control and Prevention

Fractional Dose IPV

This web page presents the background information, programmatic considerations, implementation experiences, and training materials available related to the fractional dose administration of inactivated polio vaccine (IPV). This is a resource for …

Author: World Health Organization

Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study

This article, published in The Journal of Infectious Diseases, describes how immunization regimens, including a delayed fractional third dose, were assessed for potential increased protection against malaria and immunologic responses. The authors …

Author: Regules JA, Cicatelli SB, Bennett JW, et al.

Publication date: 2016

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