Comparison of Strategies and Incidence Thresholds for Vi Conjugate Vaccines Against Typhoid Fever: A Cost-Effectiveness Modeling Study
This article, published in the Journal of Infectious Diseases, reports the results of a study that aimed to identify the strategies and associated epidemiologic conditions under which typhoid Vi conjugate vaccines (TCVs) would be cost-effective. The authors developed an age-structured transmission and cost-effectiveness model that simulated multiple vaccination strategies with a TCV. They found that TCVs would be highly cost-effective in low-income countries in settings of moderate typhoid incidence. The results were sensitive to case-fatality rates, underscoring the need to consider factors contributing to typhoid mortality, such as healthcare access and drug-resistant typhoid, in the global vaccination strategy.
Author: Lo NC, Gupta R, Stanaway JD, et al.
» Visit web page (English)
(Located at academic.oup.com)
Citation: Lo NC, Gupta R, Stanaway JD, et al. Comparison of Strategies and Incidence Thresholds for Vi Conjugate Vaccines Against Typhoid Fever: A Cost-Effectiveness Modeling Study. Journal of Infectious Diseases. 2018;Early Online Publication.
Resource types: Peer-reviewed journal