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Effectiveness of Monovalent Rotavirus Vaccine Against Hospitalization With Acute Rotavirus Gastroenteritis in Kenyan Children

This article, published in Clinical Infectious Diseases, describes an effectiveness study of monovalent rotavirus vaccine in Kenya before and after vaccine introduction in 2014. Overall two-dose vaccine effectiveness was found to be 64 percent and protection was sustained beyond infancy. Among underweight, stunted, or wasted children, vaccine effectiveness was significantly lower, highlighting the potential for nutritional interventions to maximize rotavirus vaccine performance. The authors conclude that routine rotavirus vaccination provides significant protection against rotavirus in Kenya.

Author: Khagayi S, Omore R, Otieno GP, et al.

Published: 2019

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Khagayi S, Omore R, Otieno GP, et al. Effectiveness of Monovalent Rotavirus Vaccine Against Hospitalization With Acute Rotavirus Gastroenteritis in Kenyan Children. Clinical Infectious Diseases. 2019;Early Online Publication. 

Resource types: Peer-reviewed journal

Diseases/vaccines: Rotavirus

Topics: Vaccine safety and performance, Disease/vaccine specific information

Regions: Africa