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Causes of Severe Pneumonia Requiring Hospital Admission in Children Without HIV Infection From Africa and Asia: The PERCH Multi-Country Case-Control Study

This article, published in The Lancet, reports the results of a study to estimate the causes of pneumonia in young African and Asian children. Results indicate that in low- and low-middle-income settings with widespread uptake of Haemophilus influenzae type b and pneumococcal conjugate vaccines, viruses, especially respiratory syncytial virus, were the predominant cause of pneumonia; bacteria continued to cause between a quarter to a third of all cases. The authors conclude that a small set of pathogens account for most cases of pneumonia requiring hospital admission in young children, and preventing and treating a subset of pathogens could substantially affect childhood pneumonia outcomes.

Author: The Pneumonia Etiology Research for Child Health (PERCH) Study Group

Published: 2019

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(Located at www.thelancet.com)

Citation: The Pneumonia Etiology Research for Child Health (PERCH) Study Group. Causes of Severe Pneumonia Requiring Hospital Admission in Children Without HIV Infection From Africa and Asia: The PERCH Multi-Country Case-Control Study. The Lancet. 2019;Early Online Publication.

Resource types: Peer-reviewed journal

Diseases/vaccines: Pneumococcus, Influenza, Respiratory syncytial virus (RSV)

Topics: Disease burden and surveillance, Disease/vaccine specific information

Regions: Africa, Asia