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Is One Dose of Human Papillomavirus Vaccine as Effective as Three?: A National Cohort Analysis

This article, published in Papillomavirus Research, reports the results of a study that assessed the effectiveness of quadrivalent human papillomavirus (HPV) vaccine by number of doses against precancerous cervical lesions/cancer in Australia up to seven years post vaccination. The results indicate that one dose of HPV vaccine had comparable effectiveness as two or three doses in preventing high–grade disease in a high coverage setting. These results support the hypothesis that one dose vaccination may be a viable strategy when working toward the global elimination of cervical cancer.

Author: Brotherton JML, Budd A, Rompotis C, et al.

Published: 2019

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(Located at www.sciencedirect.com)

Citation: Brotherton JML, Budd A, Rompotis C, et al. Is One Dose of Human Papillomavirus Vaccine as Effective as Three?: A National Cohort Analysis. Papillomavirus Research. 2019;8:100177.

Resource types: Peer-reviewed journal

Diseases/vaccines: Human papillomavirus (HPV)

Topics: Vaccine safety and performance, Disease/vaccine specific information

Regions: Global